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New paper out from Jewett lab on cell-free biosynthesis of limonene using enzyme-enriched Escherichia coli lysates
Isoprenoids are an attractive class of metabolites for enzymatic synthesis from renewable substrates. However, metabolic engineering of microorganisms for monoterpenoid production is limited by the need for time-consuming, and often non-intuitive, combinatorial tuning of biosynthetic pathway variations to meet design criteria. Towards alleviating this limitation, the goal of this work was to build a modular, cell-free platform for construction and testing of monoterpenoid pathways, using the fragrance and flavoring molecule limonene as a model.
Located in News
Biohackathon 2017 'Decentralised Biology' is open for applications
Whatever your discipline or age Biohackathon 2017 is open to all and encourages diverse people of any age, coming up with diverse solutions, from any discipline. Whether you are a designer, artist, actor, scientist, MBA, engineer, mathematician or programmer you are welcome to apply.
Located in News
March Cell-free Syn Bio Lunch Meeting
The SynBio SRI is pleased to announce a monthly lunch meeting series on cell-free synthetic biology, bringing together researchers and students leading or contributing to cell-free related projects. This month, we'll be joined by Dr. Trevor Hallam, Chief Scientific Officer of Sutro Biopharma.
Located in Events
July Cell-free Syn Bio Lunch Meeting
The SynBio SRI is pleased to announce a monthly lunch meeting series on cell-free synthetic biology, bringing together researchers and students leading or contributing to cell-free related projects.
Located in Events
August Cell-Free Syn Bio Lunch Meeting
The SynBio SRI is pleased to announce a monthly lunch meeting series on cell-free synthetic biology, bringing together researchers and students leading or contributing to cell-free related projects. More details TBC.
Located in Events
September Cell-Free Syn Bio Lunch
The SynBio SRI is pleased to announce a monthly lunch meeting series on cell-free synthetic biology, bringing together researchers and students leading or contributing to cell-free related projects. More details TBC.
Located in Events
Try a protein cell-free expression system for free with Quentin Dudley, OpenPlant fund grantee [Deadline: June 1 2018]
Quentin Dudley, postdoc with Nicola Patron (EI) and Sarah O'Connor (JIC) has established an in-house E.coli CFPS system to test a range of different proteins from various plants. He's looking for researchers to contribute their plant gene of interest in exchange for the output protein.
Located in News
Cell-free protein synthesis of plant proteins workshop
This workshop will be held to demonstrate a few of the nuances of setting up a cell-free reaction for Cambridge participants in the OpenPlant project- though all are welcome! Get practical hands-on experience of handling cell-free reagents.
Located in Events
Development i-Teams Final Presentation inc. Exploring potential global health applications of cell-free synthetic biology
A team of eight students and postdocs from across all five schools have been exploring potential global health applications of cell-free synthetic biology as part of the Development i-Teams programme - come and hear their conclusions!
Located in Events
Programmable biology in the test tube: new interdisciplinary activity series launched by SRI
In vitro or cell-free synthetic biology is a topic of growing interest to many groups in Cambridge and the Synthetic Biology SRI is pleased to announce an upcoming programme of activities to promote and support interdisciplinary work in this space.
Located in News