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Synthetic Biology in Cambridge

 

Biography

I am a postdoctoral researcher at the University of Cambridge focused on microbial biochemistry and infection biology. I have a keen interest in both the mechanistic and regulatory aspects of virulence in opportunistic human pathogens.

Research

Infection Biology, Biomarkers, Systems Biology, Metabolic Engineering

Publications

Key publications: 

Dolan S.K, Bock, T., Hering, V., Jones, G.W, Blankenfeldt W., Doyle S. (2017) Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus. Open Biology. doi: 10.1098/rsob.160292

 

Doyle, S., Jones, G.W, and Dolan S.K*. (2017) Dysregulated gliotoxin biosynthesis attenuates the production of unrelated metabolites in Aspergillus fumigatus. Fungal Biology. doi: 10.1016/j.funbio.2017.12.007.

 

Dolan, S. K., Owens, R. A., O’Keeffe, G., Hammel, S., Fitzpatrick, D. A, Jones, G. W., and Doyle, S. (2014) Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Gliotoxin Biosynthesis in Aspergillus fumigatus. Cell Chemistry and Biology. 21, 999–1012. doi:10.1016/j.chembiol.2014.07.006

Postdoctoral Researcher
Dr. Stephen  Dolan
Not available for consultancy

Affiliations

Classifications: 
Departments and institutes: