Biography
Discovered early that building biological systems was more exciting to me than only studying them, and followed that idea - which has led me to laboratory automation and high-throughput screening & selection methods. And more recently into playing with hardware design, electronics & software.
Research
Engineering strains, genomes, complex molecular machines, such as the ribosome, and enzymes. Applications for laboratory automation.
Publications
Key publications:
Fried, S., Schmied, W. H., Uttamapinant, C., & Chin, J. W. (2015). Ribosome Subunit Stapling for Orthogonal Translation in E. coli. Angewandte Chemie.
Schmied, W. H., Elsässer, S. J., Uttamapinant, C., & Chin, J. W. (2014). Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1. Journal of the American Chemical Society, 136(44), 15577–83.
